Phase-and disorder-specific differences in peripheral metabo…
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- DOI 10.1080/15622975.2023.2169348
- PMID https://pubmed.ncbi.nlm.nih.gov/36648064
- OpenAlex ID W4316813225
- Type Article
- Language EN
- Published 17 Jan 2023
- Volume 24 (7)
- Pages 564–577
- Source The World Journal of Biological Psychiat…
- Publisher Taylor & Francis
- FWCI 1.00
- Countries 2
- Institutions 9
- Added 10 Oct 2025
- Updated 20 Oct 2026
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Phase-and disorder-specific differences in peripheral metabolites of the kynurenine pathway in major depression, bipolar affective disorder and schizophrenia
Article 2023 EN
OBJECTIVES: Kynurenine, kynurenic and quinolinic acid are important metabolites in tryptophan metabolism. Due to an involvement in glutamatergic neurotransmission and immune response, previous studies have investigated this pathway in mental disorders such as major depressive disorder (MDD), bipolar disorder (BD) or schizophrenia (SCZ). Tryptophan and kynurenine have been shown to be decreased acr…
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12 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Murielle Brum | Goethe University Frankfurt (DE) University Hospital Frankfurt (DE) | — |
| 2 | Matthias Nieberler | University of Würzburg (DE) Universitätsklinikum Würzburg (DE) | |
| 3 | Christopher Kehrwald | Goethe University Frankfurt (DE) University Hospital Frankfurt (DE) | — |
| 4 | Katrin Knopf | Goethe University Frankfurt (DE) University Hospital Frankfurt (DE) | — |
| 5 | Nathalie Brunkhorst-Kanaan | Goethe University Frankfurt (DE) University Hospital Frankfurt (DE) | — |
| 6 | Semra Etyemez | Goethe University Frankfurt (DE) Johns Hopkins University (US) +2 | |
| 7 | Kelly Ann Allers | Boehringer Ingelheim (Germany) (DE) | |
| 8 | Robert A. Bittner | Goethe University Frankfurt (DE) Max Planck Society (DE) +2 | |
| 9 | David Anthony Slattery | Goethe University Frankfurt (DE) University Hospital Frankfurt (DE) | |
| 10 | Rhiannon Victoria McNeill | Goethe University Frankfurt (DE) University of Würzburg (DE) +2 | |
| 11 | Andreas Reif | Goethe University Frankfurt (DE) University Hospital Frankfurt (DE) | |
| 12 | Sarah Kittel‐Schneider Corresponding | Goethe University Frankfurt (DE) University of Würzburg (DE) +2 |
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