Central kynurenine pathway shift with age in women

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83
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2015
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  • DOI 10.1111/jnc.13496
  • PMID https://pubmed.ncbi.nlm.nih.gov/26670548
  • OpenAlex ID W2209613548
  • Type Article
  • Language EN
  • Published 16 Dec 2015
  • Volume 136 (5)
  • Pages 995–1003
  • Source Journal of Neurochemistry
  • Publisher Wiley
  • FWCI 0.84
  • Countries 1
  • Institutions 4
  • Added 10 Oct 2025
  • Updated 11 Oct 2026
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Central kynurenine pathway shift with age in women

Article 2015 EN

Age is considered a dominant risk factor in the development of most neurodegenerative disorders. The kynurenine pathway, a major metabolic pathway of tryptophan is altered in the majority of neurodegenerative disorders. In this study, we have analysed CSF samples from 49 healthy women across a wide age range (0-90) for kynurenine pathway metabolites and the inflammatory marker neopterin. Our resul…

83

Citations

25

References

4

Authors

0.84

FWCI

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UN Sustainable Development Goals
1 SDGs
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4 authors
#AuthorInstitutionsORCID
1 Josien de Bie Macquarie University (AU)
2 Jade Guest Sydney Adventist Hospital (AU) UNSW Sydney (AU) —
3 Gilles J. Guillemin Corresponding Macquarie University (AU)
4 Ross Grant Corresponding The University of Sydney (AU) Sydney Adventist Hospital (AU) +1
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