L -kynurenine: metabolism and mechanism of neuroprotection
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Refs2008
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- DOI 10.2217/14796708.3.2.169
- OpenAlex ID W2104241569
- Type Article
- Language EN
- Published 27 Feb 2008
- Volume 3 (2)
- Pages 169–188
- Source Future Neurology
- Publisher Future Medicine
- FWCI 1.24
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 14 Oct 2026
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L -kynurenine: metabolism and mechanism of neuroprotection
Article 2008 EN
L-kynurenine is an intermediate in the pathway of the metabolism of L-tryptophan to nicotinic acid. L-kynurenine is formed in the mammalian brain (40%) and is taken up from the periphery (60%), indicating that it can be transported across the BBB. It was discovered some 30 years ago that compounds in the kynurenine family have neuroactive properties. L-kynurenine, the central agent of this pathway…
34
Citations
216
References
3
Authors
1.24
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Hermina Robotka | University of Szeged (HU) | |
| 2 | József Toldi | University of Szeged (HU) | |
| 3 | László Vécsei | University of Szeged (HU) |
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