The role of the kynurenine pathway and quinolinic acid in ad…

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  • DOI 10.1111/ijcp.13739
  • PMID https://pubmed.ncbi.nlm.nih.gov/32997876
  • OpenAlex ID W3090431934
  • Type Article
  • Language EN
  • Published 30 Sep 2020
  • Volume 75 (4)
  • Pages e13739
  • Source International Journal of Clinical Practi…
  • Publisher Wiley
  • FWCI 1.01
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 22 Oct 2026
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The role of the kynurenine pathway and quinolinic acid in adolescent major depressive disorder

Article 2020 EN Bronze

BACKGROUND: The biological mechanisms underlying major depressive disorder (MDD) are not yet sufficiently understood. The kynurenine pathway has been proposed to play a key role between peripheral inflammation and alterations in the central nervous system. This is because of reduced usability of tryptophan (TRP) and production of oxygen radicals and highly potent neurotoxic agents in this pathway.…

48

Citations

53

References

5

Authors

1.01

FWCI

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
5 authors
#AuthorInstitutionsORCID
1 Masum Öztürk Corresponding —
2 Şermin Yalın Sapmaz Manisa Celal Bayar University (TR)
3 Hasan Kandemır Manisa Celal Bayar University (TR)
4 Fatma Taneli Manisa Celal Bayar University (TR)
5 Ömer Aydemır Manisa Celal Bayar University (TR)

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