Lipopolysaccharide induces interleukin-6 release from rat pe…
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- PMID https://pubmed.ncbi.nlm.nih.gov/7505726
- OpenAlex ID W33640526
- Type Article
- Language EN
- Published 01 Nov 1993
- Volume 41 (3)
- Pages 131–7
- Source PubMed
- Publisher National Institutes of Health
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 16 Oct 2026
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Lipopolysaccharide induces interleukin-6 release from rat peritoneal macrophages in vitro: evidence for a novel mechanism.
Article 1993 EN
Interleukin-6 (IL-6) is a cytokine involved in the terminal differentiation of B-cells, T-cell activation, and secretion of hepatic acute phase proteins. The production of IL-6 is regulated by many factors, including IL-1 and lipopolysaccharide (LPS). Because IL-6 may be an important contributor to the effects of LPS in inflammation and septic shock, we investigated the ability of LPS to induce IL…
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3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | R M Wright | Medical University of South Ca… (US) | — |
| 2 | Charles Holladay | — | — |
| 3 | B L Spangelo | — | — |
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