Dose‐dependent Immunomodulatory Effects of Acetylsalicylic A…

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Dose‐dependent Immunomodulatory Effects of Acetylsalicylic Acid and Indomethacin in Human Whole Blood: Potential Role of Cyclooxygenase‐2 Inhibition

Article 2004 EN Bronze

The aim of the study was to characterize the in vitro effect of non-steroidal anti-inflammatory drugs (NSAIDs) on the production of pro-inflammatory cytokines in a human whole blood assay. Whole blood samples were pre-incubated with acetylsalicylic acid, indomethacin, selective cyclooxygenase (COX)-1 inhibitor (SC-560), COX-2 inhibitor (NS-398) or prostaglandin E2 (PGE2) before stimulation with li…

45

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5

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1.18

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5 authors
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1 Christoph Härtel University of Lübeck (DE)
2 J. Von Puttkamer University of Lübeck (DE) —
3 F. Gallner University of Lübeck (DE) —
4 Tobias Strunk University of Lübeck (DE)
5 C. Schultz Corresponding University of Lübeck (DE) —

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