Female Sex Hormones Influence the Febrile Response Induced b…

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Female Sex Hormones Influence the Febrile Response Induced by Lipopolysaccharide, Cytokines and Prostaglandins but not by Interleukin‐1β in Rats

Article 2016 EN

There are differences in the immune response, and particularly fever, between males and females. In the present study, we investigated how the febrile responses induced by lipopolysaccharide (LPS) and different endogenous pyrogens were affected by female gonadal hormones. The febrile response to i.p. injection ofLPS(50 μg/kg) was 40% lower in female rats compared to male or ovariectomised (OVX) fe…

18

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51

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8

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8 authors
#AuthorInstitutionsORCID
1 Haissa Oliveira Brito Universidade Federal do Paraná (BR)
2 Débora Rasec Radulski Universidade Federal do Paraná (BR)
3 Daniel Wilhelms Linköping University (SE)
4 Andrea Stojakovic Linköping University (SE)
5 Luciane Maria Oliveira Brito Universidade Federal do Maranh… (BR)
6 David Engblom Linköping University (SE)
7 Célia Regina Cavichiolo Franco Universidade Federal do Paraná (BR)
8 Aleksander Roberto Zampronio Corresponding Universidade Federal do Paraná (BR)

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