Dominant substitutions underlying the antigenic evolution of…

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Dominant substitutions underlying the antigenic evolution of H5 influenza virus

Article 2025 EN Gold

Abstract Highly pathogenic avian influenza (HPAI) H5 viruses have recently been documented in mammals including humans, posing a major threat to global public health. To prevent a potential H5 pandemic, it is critical to elucidate the antigenic evolutionary pattern and identify key drivers underlying its evolution. In this study, we constructed a comprehensive antigenic map of H5 influenza viruses…

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16 authors
#AuthorInstitutionsORCID
1 Mengyi Zhang Chinese Academy of Medical Sci… (CN) National Institutes for Food a… (CN) —
2 Luyao Qin Chinese Academy of Medical Sci… (CN) Suzhou Institute of Systems Me… (CN) —
3 Zichen Li Chinese Academy of Medical Sci… (CN) —
4 Jiamin Chen Chinese Academy of Medical Sci… (CN)
5 Jincheng Tong Chinese Academy of Medical Sci… (CN) —
6 Xiao Ding Chinese Academy of Medical Sci… (CN) Suzhou Institute of Systems Me… (CN) —
7 Huan Li Chinese Academy of Medical Sci… (CN) —
8 Yun Ma Chinese Academy of Medical Sci… (CN) Suzhou Institute of Systems Me… (CN)
9 Jingze Liu Chinese Academy of Medical Sci… (CN) Suzhou Institute of Systems Me… (CN) —
10 Qiuju He Chinese Academy of Medical Sci… (CN) —
11 Rong Bi Chinese Academy of Medical Sci… (CN) —
12 Weijin Huang Chinese Academy of Medical Sci… (CN) National Institutes for Food a… (CN)
13 Cheng Bian Chinese Academy of Medical Sci… (CN)
14 Youchun Wang Corresponding Chinese Academy of Medical Sci… (CN)
15 Aiping Wu Corresponding Chinese Academy of Medical Sci… (CN) Suzhou Institute of Systems Me… (CN)
16 Qianqian Li Corresponding Chinese Academy of Medical Sci… (CN)

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