Mapping Haemagglutinin Residues Driving Antigenic Diversity …

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  • DOI 10.1101/2025.06.18.660338
  • OpenAlex ID W4411408321
  • Type Preprint
  • Language EN
  • Published 18 Jun 2025
  • Source bioRxiv (Cold Spring Harbor Laboratory)
  • Publisher Cold Spring Harbor Laboratory
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 28 Oct 2026
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Mapping Haemagglutinin Residues Driving Antigenic Diversity in H5Nx Avian Influenza Viruses

Preprint 2025 EN Green

Abstract Since its emergence in 1996, the H5 avian influenza virus (AIV) A/Goose/Guangdong/1/1996 (Gs/GD) haemagglutinin (HA) has evolved into over 30 genetically and antigenically distinct clades, including the widespread clade 2.3.4.4b. Vaccination is widely used in endemic regions to reduce poultry losses and zoonotic risk. However, the evolving antigenic diversity and global co-circulation of…

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UN Sustainable Development Goals
1 SDGs
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4 authors
#AuthorInstitutionsORCID
1 Rebecca Daines The Pirbright Institute (GB) Royal Veterinary College (GB)
2 Jean-Rémy Sadeyen The Pirbright Institute (GB)
3 Pengxiang Chang The Pirbright Institute (GB)
4 Munir Iqbal Corresponding The Pirbright Institute (GB)
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