A canine insulinoma with amphicrine differentiation: morphol…

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A canine insulinoma with amphicrine differentiation: morphological and immunohistochemical characteristics

Article 2025 EN Diamond

A 10-year-old male toy poodle presented with hypoglycemia. An insulinoma was suspected and a surgical excision of two pancreatic masses was performed. White-gray, demarcated, soft masses were identified in the pancreas. Histopathologically, two types of growth patterns were observed in the same neoplasm: nest and glandular. To investigate cellular differentiation, we performed immunohistochemical…

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6 authors
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1 Hisaki Tokuno Osaka Metropolitan University (JP) —
2 Masashi Fujimoto — —
3 Makoto Tsuji —
4 Miyuu Tanaka Osaka Metropolitan University (JP)
5 Takeshi Izawa Osaka Metropolitan University (JP)
6 Mitsuru Kuwamura Corresponding Osaka Metropolitan University (JP)

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