Virtual Docking Screening and QSAR Studies to Explore PI3K a…
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- DOI 10.26502/jcsct.5079099
- OpenAlex ID W3116479654
- Type Article
- Language EN
- Published 01 Jan 2020
- Volume 05 (01)
- Source Journal of Cancer Science and Clinical T…
- FWCI 0.12
- Added 10 Oct 2025
- Updated 06 Nov 2025
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Virtual Docking Screening and QSAR Studies to Explore PI3K and mTOR Inhibitors Acting on AKT in Cancers
Article 2020 EN Diamond
The PI3K / AKT / mTOR pathway is an important regulator of a wide range of cellular processes including survival, proliferation, growth, metabolism, angiogenesis and metastasis. PI3K induces translocation of Ser / Thr Akt kinase, Akt is activated by PDK1 and mTOR2-dependent phosphorylations. Aberrant activation of the PI3K / AKT / mTOR pathway is frequently observed in many human malignancies and…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Ilham Kandoussi | — | |
| 2 | Oussama Benherrif | — | — |
| 3 | Wiame Lakhlili | — | — |
| 4 | Jamal Taoufik | — | — |
| 5 | Azeddine Ibrahimi | — |
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