Protective effects of inhibition of adenosine monophosphate activated protein kinase activity against cerebral ischemia-reperfusion injury in mice

Objective To observe the effect of inhibition of adenosine monophosphate activated protein kinase (AMPK) on shape，function and inflammatory factor of microglia for mice after cerebral ischemia-reperfusion injury and the action mechanism of AMPK inhibition on neuroprotective effects. Methods One hundred and twenty male Kunming mice were randomly divided into sham group，ischemia-reperfusion g…