Effect of propofol on expressions of TNF-α,IL-10 and NF-κB in rat cerebrum undergoing ischemia and reperfusion

Objective To study the effects of propofol on the expressions of tumor necrosis factor(TNF)-α,interleukin-10(IL-10)and nuclear factor-κB(NF-κB)in rat cerebrum undergoing ischemia and reperfusion.Methods Thirty rats were randomly divided into five groups with 6 rats each.The rats in group S accepted sharm operation as the controls,in group IR focal cerebral ischemia by temporary bilateral carotid a…