Tryptophan metabolism and oxidative stress in patients with …
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- DOI 10.1111/j.1471-4159.2005.03070.x
- PMID https://pubmed.ncbi.nlm.nih.gov/15836620
- OpenAlex ID W2157059809
- Type Article
- Language EN
- Published 04 Apr 2005
- Volume 93 (3)
- Pages 611–623
- Source Journal of Neurochemistry
- Publisher Wiley
- FWCI 3.74
- Countries 1
- Institutions 3
- Added 10 Oct 2025
- Updated 14 Oct 2026
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Tryptophan metabolism and oxidative stress in patients with Huntington's disease
Article 2005 EN
Abnormalities in the kynurenine pathway may play a role in Huntington's disease (HD). In this study, tryptophan depletion and loading were used to investigate changes in blood kynurenine pathway metabolites, as well as markers of inflammation and oxidative stress in HD patients and healthy controls. Results showed that the kynurenine : tryptophan ratio was greater in HD than controls in the baseli…
310
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7
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1 SDGsAuthors & Affiliations
7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Nicholas S. Stoy | Royal Hospital for Neuro-disab… (GB) | — |
| 2 | Gillian Mackay | Royal Hospital for Neuro-disab… (GB) Epsom Hospital (GB) +1 | |
| 3 | Caroline M. Forrest | Royal Hospital for Neuro-disab… (GB) Epsom Hospital (GB) +1 | — |
| 4 | J A Christofides | Royal Hospital for Neuro-disab… (GB) Epsom Hospital (GB) +1 | — |
| 5 | Martyn Egerton | Royal Hospital for Neuro-disab… (GB) Epsom Hospital (GB) +1 | — |
| 6 | Trevor W. Stone | Royal Hospital for Neuro-disab… (GB) Epsom Hospital (GB) +1 | |
| 7 | Lynda Gail Darlington | Royal Hospital for Neuro-disab… (GB) Epsom Hospital (GB) +1 | — |
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