Evidence that in vivo constriction of cerebral arterioles by…

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1987
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Evidence that in vivo constriction of cerebral arterioles by local application of tert-butyl hydroperoxide is mediated by release of endogenous thromboxane.

Article 1987 EN Bronze

Pial arterioles of mice were suffused in situ with tert-butyl hydroperoxide (TBHP). This agent has been reported to stimulate synthesis or release of the constrictor, thromboxane. In the present study we observed pial arterioles by in vivo microscopy. Locally applied TBHP produced dose-dependent constriction, significantly inhibited by each of three drugs: acetylsalicylic acid, OKY-046, and SQ-295…

9

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16

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2

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0.42

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1 SDGs
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2 authors
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1 William I. Rosenblum —
2 D Bryan — —

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