Thromboxane-induced pulmonary vasoconstriction: involvement …

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1985
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  • DOI 10.1152/jappl.1985.58.1.34
  • PMID https://pubmed.ncbi.nlm.nih.gov/3917993
  • OpenAlex ID W2166801651
  • Type Article
  • Language EN
  • Published 01 Jan 1985
  • Volume 58 (1)
  • Pages 34–44
  • Source Journal of Applied Physiology
  • Publisher American Physiological Society
  • FWCI 1.68
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 02 Oct 2026
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Thromboxane-induced pulmonary vasoconstriction: involvement of calcium

Article 1985 EN

Infusion of tert-butyl hydroperoxide (t-bu-OOH) or arachidonic acid into rabbit pulmonary arteries stimulated thromboxane B2 (TxB2) production and caused pulmonary vasoconstriction. Both phenomena were blocked by cyclooxygenase inhibitors or a thromboxane synthase inhibitor. The increase in pulmonary arterial pressure caused by either t-bu-OOH or arachidonic acid infusion correlated with the conce…

58

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0

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5

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1.68

FWCI

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5 authors
#AuthorInstitutionsORCID
1 Imad S. Farrukh Johns Hopkins University (US) —
2 J. R. Michael Johns Hopkins University (US) —
3 W. R. Summer Johns Hopkins University (US) —
4 N. Franklin Adkinson — —
5 G. H. Gurtner — —

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