The role of prostanoid receptors in mediating the effects of…

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The role of prostanoid receptors in mediating the effects of PGE2on human platelet function

Article 2010 EN

The effects of prostaglandin E(2) (PGE(2)) on platelet function are believed to be the result of opposing mechanisms that lead to both enhancement and inhibition of platelet function. Enhancement of platelet function is known to be via EP3 receptors linked to G(i) and inhibition of adenylyl cyclase. However, the receptors involved in inhibition of platelet function have not been fully defined. Her…

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6 authors
#AuthorInstitutionsORCID
1 David Iyú Corresponding University of Nottingham (GB)
2 Jackie R. Glenn University of Nottingham (GB) —
3 Ann E. White University of Nottingham (GB) —
4 Andrew J. Johnson University of Nottingham (GB)
5 Susan C. Fox University of Nottingham (GB) —
6 Stan Heptinstall University of Nottingham (GB)

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