PI3K/Akt/mTOR Pathway: A Growth and Proliferation Pathway

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2009
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Work Details
  • DOI 10.1007/978-1-59745-332-5_15
  • OpenAlex ID W1006589974
  • Type Book-chapter
  • Language EN
  • Published 01 Jan 2009
  • Pages 267–285
  • Source Humana Press eBooks
  • Publisher Humana Press
  • FWCI 0.78
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 14 Oct 2026
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PI3K/Akt/mTOR Pathway: A Growth and Proliferation Pathway

Book-chapter 2009 EN

The phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/ mammalian target of rapamycin (mTOR) pathway regulates numerous cellular processes such as growth, proliferation, cell cycle progression, motility, adhesion, and angio-genesis, and appears to be constitutively active in a majority of renal cell carcinoma (RCC). The integrity of the pathway is clearly vital to the survival and growth of R…

22

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77

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3

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0.78

FWCI

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Keywords
UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
3 authors
#AuthorInstitutionsORCID
1 Daniel Cho Corresponding Beth Israel Deaconess Medical … (US) —
2 James Walter Mier Beth Israel Deaconess Medical … (US) —
3 Micheal B. Atkins Beth Israel Deaconess Medical … (US) —
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