Pulmonary vasoconstrictor effects of prostacyclin in rats: p…
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- DOI 10.1152/jappl.1996.81.6.2595
- PMID https://pubmed.ncbi.nlm.nih.gov/9018511
- OpenAlex ID W623431024
- Type Article
- Language EN
- Published 01 Dec 1996
- Volume 81 (6)
- Pages 2595–2603
- Source Journal of Applied Physiology
- Publisher American Physiological Society
- Countries 2
- Institutions 2
- Added 10 Oct 2025
- Updated 16 Oct 2026
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Pulmonary vasoconstrictor effects of prostacyclin in rats: potential role of thromboxane receptors
Article 1996 EN
Endogenous prostacyclin (PGI2; epoprostenol) is a potent endothelium-derived pulmonary vasodilator. However, the effects of exogenous PGI2 on isolated arteries could be either relaxant or contractile, depending on the species and organ studied. The present study investigated the distal pathways involved in the PGI2-induced contraction in rat intrapulmonary artery (PA) and relaxation in lamb PA. Wh…
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Yi-Ju Zhao | University of Maryland, Baltim… (US) Chinese Academy of Medical Sci… (CN) | — |
| 2 | Jian Wang | University of Maryland, Baltim… (US) Chinese Academy of Medical Sci… (CN) | |
| 3 | Mary L. Tod | University of Maryland, Baltim… (US) Chinese Academy of Medical Sci… (CN) | — |
| 4 | Lewis J. Rubin | University of Maryland, Baltim… (US) Chinese Academy of Medical Sci… (CN) | |
| 5 | Xiao-Jian Yuan | University of Maryland, Baltim… (US) Chinese Academy of Medical Sci… (CN) | — |
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