Fluid shear stress-induced down-regulation of miR-146a-5p in…
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- DOI 10.33549/physiolres.934922
- PMID https://pubmed.ncbi.nlm.nih.gov/36281726
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/9814977
- OpenAlex ID W4307229780
- Type Article
- Language EN
- Published 13 Oct 2022
- Volume 71 (6)
- Pages 835–848
- Source Physiological Research
- Publisher Institute of Physiology of the Czec…
- FWCI 0.95
- Countries 1
- Institutions 3
- Added 30 Oct 2022
- Updated 28 Oct 2026
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Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4
Article 2022 EN Gold
Fluid shear stress (FSS) plays an important role in osteoblast apoptosis. However, the role of miRNA in osteoblast apoptosis under FSS and possible molecular mechanisms remain unknown. Our aim of the study was to explore whether miR-146a-5p regulates osteoblast apoptosis under FSS and its molecular mechanisms. FSS could down-regulate the expression of miR-146a-5p in MC3T3-E1 cells. We confirm that…
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7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | X Liu | Lanzhou University Second Hosp… (CN) | — |
| 2 | K Zhang | Xi'an Honghui Hospital (CN) Xi'an Jiaotong University (CN) | — |
| 3 | L Wang | Lanzhou University Second Hosp… (CN) | — |
| 4 | Bin Geng | Lanzhou University Second Hosp… (CN) | |
| 5 | Z Liu | Lanzhou University Second Hosp… (CN) | — |
| 6 | Qiong Yi | Lanzhou University Second Hosp… (CN) | |
| 7 | Yayi Xia Corresponding | Lanzhou University Second Hosp… (CN) |
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