Macrophage polarity and wound age determination
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- DOI 10.1038/s41598-022-24577-9
- PMID https://pubmed.ncbi.nlm.nih.gov/36434083
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/9700750
- OpenAlex ID W4310057555
- Type Article
- Language EN
- Published 25 Nov 2022
- Volume 12 (1)
- Pages 20327
- Source Scientific Reports
- Publisher Nature Portfolio
- FWCI 5.73
- Countries 1
- Institutions 1
- Added 30 Nov 2022
- Updated 28 Oct 2026
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Macrophage polarity and wound age determination
Article 2022 EN Gold
Abstract We investigated the dynamics of the gene expression of M1 and M2 macrophage markers during skin wound healing in mice. Expression of M1-macrophage markers, such as Il12a, Tnf, Il6, Il1b, and Nos2 was upregulated after wounding and peaked at 1 or 3 days after injury, and that of M2-macrophage markers such as Mrc1, Cd163, Ccl17, Arg, and Tgfb1, peaked at 6 days after injury. Consistent with…
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1 SDGsAuthors & Affiliations
10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Yumi Kuninaka | Wakayama Medical University (JP) | |
| 2 | Yuko Ishida Corresponding | Wakayama Medical University (JP) | |
| 3 | Akiko Ishigami | Wakayama Medical University (JP) | |
| 4 | Mizuho Nosaka | Wakayama Medical University (JP) | |
| 5 | Jumpei Matsuki | Wakayama Medical University (JP) | |
| 6 | Haruki Yasuda | Wakayama Medical University (JP) | |
| 7 | Ayumi Kofuna | Wakayama Medical University (JP) | |
| 8 | Akihiko Kimura | Wakayama Medical University (JP) | |
| 9 | Fukumi Furukawa | Wakayama Medical University (JP) | |
| 10 | Toshikazu Kondo Corresponding | Wakayama Medical University (JP) |
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