Age-Related Alterations in Macrophage Distribution and Funct…

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Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing

Article 2022 EN Gold

Ageing-related delays and dysregulated inflammation in wound healing are well-documented in both human and animal models. However, cellular and molecular changes underlying this impairment in healing progression are not fully understood. In this study, we characterised ageing-associated changes to macrophages in wounds of young and aged mice and investigated transcriptomic differences that may imp…

30

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58

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10

Authors

2.38

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10 authors
#AuthorInstitutionsORCID
1 Christabel Thembela Dube Agency for Science, Technology… (SG) University of Manchester (GB)
2 Yasmin Hui Binn Ong Agency for Science, Technology… (SG)
3 Kelly Wemyss Manchester Academic Health Sci… (GB) University of Manchester (GB)
4 Siddharth Krishnan Manchester Academic Health Sci… (GB) University of Manchester (GB)
5 Tiak Ju Tan Agency for Science, Technology… (SG)
6 Baptiste Janela Agency for Science, Technology… (SG) Skin Research Institute of Sin… (SG)
7 John R. Grainger Manchester Academic Health Sci… (GB) University of Manchester (GB)
8 Matthew Ronshaugen University of Manchester (GB)
9 Kimberly A. Mace Corresponding University of Manchester (GB)
10 Chin Yan Lim Corresponding Agency for Science, Technology… (SG) National University of Singapo… (SG)

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