Age-Related Alterations in Macrophage Distribution and Funct…
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- DOI 10.3389/fimmu.2022.943159
- PMID https://pubmed.ncbi.nlm.nih.gov/35874681
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/9304927
- OpenAlex ID W4284966906
- Type Article
- Language EN
- Published 08 Jul 2022
- Volume 13
- Pages 943159
- Source Frontiers in Immunology
- Publisher Frontiers Media
- FWCI 2.38
- Countries 2
- Institutions 5
- Added 10 Jul 2022
- Updated 28 Oct 2026
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Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing
Article 2022 EN Gold
Ageing-related delays and dysregulated inflammation in wound healing are well-documented in both human and animal models. However, cellular and molecular changes underlying this impairment in healing progression are not fully understood. In this study, we characterised ageing-associated changes to macrophages in wounds of young and aged mice and investigated transcriptomic differences that may imp…
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10
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2.38
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10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Christabel Thembela Dube | Agency for Science, Technology… (SG) University of Manchester (GB) | |
| 2 | Yasmin Hui Binn Ong | Agency for Science, Technology… (SG) | |
| 3 | Kelly Wemyss | Manchester Academic Health Sci… (GB) University of Manchester (GB) | |
| 4 | Siddharth Krishnan | Manchester Academic Health Sci… (GB) University of Manchester (GB) | |
| 5 | Tiak Ju Tan | Agency for Science, Technology… (SG) | |
| 6 | Baptiste Janela | Agency for Science, Technology… (SG) Skin Research Institute of Sin… (SG) | |
| 7 | John R. Grainger | Manchester Academic Health Sci… (GB) University of Manchester (GB) | |
| 8 | Matthew Ronshaugen | University of Manchester (GB) | |
| 9 | Kimberly A. Mace Corresponding | University of Manchester (GB) | |
| 10 | Chin Yan Lim Corresponding | Agency for Science, Technology… (SG) National University of Singapo… (SG) |
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