Piezo2 Mechanosensitive Ion Channel Role in Primary Enteroch…

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2018
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  • DOI 10.1096/fasebj.2018.32.1_supplement.868.3
  • OpenAlex ID W3177313502
  • Type Article
  • Language EN
  • Published 01 Apr 2018
  • Volume 32 (S1)
  • Source The FASEB Journal
  • Publisher Wiley
  • Countries 1
  • Institutions 2
  • Added 05 Jul 2021
  • Updated 22 Sep 2026
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Piezo2 Mechanosensitive Ion Channel Role in Primary Enterochromaffin (EC) Cell Mechanosensitivity

Article 2018 EN

INTRODUCTION Intestinal enterochromaffin (EC) cells are the specialized epithelial mechanosensors of the gastrointestinal (GI) epithelium and are functionally and developmentally like Merkel cells in the skin. EC cells release serotonin (5‐HT) in response to mechanical stimuli. Recently, we discovered that like Merkel cells, human and mouse EC cells express the mechanosensitive (MS) ion channel Pi…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
8 authors
#AuthorInstitutionsORCID
1 Constanza Alcaino Mayo Clinic (US)
2 Kaitlyn R. Knutson Mayo Clinic (US)
3 Gulcan Yildiz Mayo Clinic (US)
4 David Robert Linden Mayo Clinic (US)
5 Joyce H. Li University of Massachusetts Ch… (US)
6 Andrew B. Leiter University of Massachusetts Ch… (US)
7 Gianrico Farrugia Mayo Clinic (US)
8 Arthur Beyder Mayo Clinic (US)

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