Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4
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- DOI 10.1080/19336950.2017.1279370
- PMID https://pubmed.ncbi.nlm.nih.gov/28085630
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/5463886
- OpenAlex ID W2575510219
- Type Article
- Language EN
- Published 13 Jan 2017
- Volume 11 (3)
- Pages 245–253
- Source Channels
- Publisher Taylor & Francis
- FWCI 3.25
- Countries 1
- Institutions 2
- Added 26 Jan 2017
- Updated 29 Oct 2026
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Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4
Article 2017 EN Gold
Enterochromaffin (EC) cells are the primary mechanosensors of the gastrointestinal (GI) epithelium. In response to mechanical stimuliEC cells release serotonin (5-hydroxytryptamine; 5-HT). The molecular details ofEC cell mechanosensitivity are poorly understood. Recently, our group found that human and mouseEC cells express the mechanosensitive ion channel Piezo2. The mechanosensitive currents in…
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44
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5
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3.25
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Constanza Alcaino | Mayo Clinic (US) | |
| 2 | Kaitlyn R. Knutson | Mayo Clinic (US) | |
| 3 | Philip A. Gottlieb | University at Buffalo, State U… (US) | |
| 4 | Gianrico Farrugia | University at Buffalo, State U… (US) | |
| 5 | Arthur Beyder Corresponding | Mayo Clinic (US) |
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