Difficulties of Translating Outcomes from Animal Studies to …
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- DOI 10.1039/9781788012539-00051
- OpenAlex ID W2769927728
- Type Book-chapter
- Language EN
- Published 17 Nov 2017
- Pages 51–63
- Source Royal Society of Chemistry eBooks
- Publisher Royal Society of Chemistry
- Countries 2
- Institutions 2
- Added 10 Oct 2025
- Updated 10 Oct 2026
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Difficulties of Translating Outcomes from Animal Studies to Clinical Trials
Book-chapter 2017 EN
Attempts to reproduce the findings of experimental treatments for stroke in animal models have been mainly unsuccessful. This review considers possible reasons for this failure to translate from animals to humans. Differences among animal models of stroke, transient ischemic attack, and traumatic brain injury in the type and extent of cerebral injury are reviewed, as well as differences between hu…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Philip V. Peplow | University of Otago (NZ) | |
| 2 | Bridget Martinez | University of California, Merc… (US) |
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