Endothelin Release and Shift in Prostaglandin Balance Are In…

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DOI 10.1097/00005344-199204002-00009
PMID https://pubmed.ncbi.nlm.nih.gov/1282978
OpenAlex ID W2315329949
Type Article
Language EN
Published 01 Apr 1992
Volume 20
Pages S25–S28
Source Journal of Cardiovascular Pharmacology
Publisher Lippincott Williams & Wilkins
FWCI 1.45
Countries 1
Institutions 1
Added 24 Jun 2016
Updated 27 Oct 2026

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Endothelin Release and Shift in Prostaglandin Balance Are Involved in the Modulation of Vascular Tone by Recombinant Erythropoietin

Article 1992 EN

Hypertension is the main side effect developing in patients suffering from renal anemia who are treated with recombinant human erythropoietin (rhEPO). We investigated the effect of rhEPO on the vascular tone of rabbit aorta. rhEPO had no direct vasoconstrictor effect, but it enhanced norepinephrine (NE)-induced contractions of rabbit aortic rings. Relaxations to acetylcholine (ACh, 1 microM) were…

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5 authors

#	Author	Institutions	ORCID
1	Stefanie M. Bode‐Böger Corresponding	Medizinische Hochschule Hannov… (DE)
2	Rainer H. Böger Corresponding	Medizinische Hochschule Hannov… (DE)
3	Michaela Kühn	Medizinische Hochschule Hannov… (DE)
4	Jörg Radermacher	Medizinische Hochschule Hannov… (DE)
5	Jürgen C. Frölich	Medizinische Hochschule Hannov… (DE)	—

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