Thromboxane A2 in severe hypertension and stroke in stroke-p…

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1988
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Thromboxane A2 in severe hypertension and stroke in stroke-prone spontaneously hypertensive rats.

Article 1988 EN Bronze

Thromboxane A2 is a prostanoid having potent platelet aggregatory and vasoconstrictor properties. To determine a possible role for thromboxane A2 in the development of severe hypertension and stroke, we chronically administered the selective thromboxane A2 synthase inhibitor UK-38,485 (Dazmegrel) to stroke-prone spontaneously hypertensive rats (SHRSP). Serum thromboxane B2 (the stable hydrolysis p…

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3 authors
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1 Charles T. Stier New York Medical College (US)
2 Ibrahim F. Benter New York Medical College (US)
3 S Levine New York Medical College (US) —

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