Reversal of delayed vasospasm by TS-011 in the dual hemorrha…

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Reversal of delayed vasospasm by TS-011 in the dual hemorrhage dog model of subarachnoid hemorrhage.

Article 2006 EN Green

PURPOSE: Arachidonic acid is avidly metabolized to a potent vasoconstrictor, 20-hydroxyeicosatetraenoic acid (20-HETE), in the cerebral circulation. 20-HETE has been reported to contribute to the acute fall in cerebral blood flow following subarachnoid hemorrhage (SAH), but its role in the development of delayed vasospasm is unknown. The present study examined whether delayed vasospasm is associat…

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8 authors
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1 Lotfi Hacein‐Bey Medical College of Wisconsin (US)
2 David Rae Harder — —
3 H T Meier — —
4 Panayiotis N. Varelas —
5 N Miyata — —
6 Kathryn K. Lauer —
7 Joseph F. Cusick — —
8 Richard J. Roman —

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