Evidence that 20-HETE contributes to the development of acut…
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- DOI 10.1179/016164106x152016
- PMID https://pubmed.ncbi.nlm.nih.gov/17164037
- OpenAlex ID W2087723973
- Type Article
- Language EN
- Published 01 Oct 2006
- Volume 28 (7)
- Pages 738–749
- Source Neurological Research
- Publisher Taylor & Francis
- FWCI 2.71
- Countries 1
- Institutions 3
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Evidence that 20-HETE contributes to the development of acute and delayed cerebral vasospasm
Article 2006 EN
Recent studies have indicated that arachidonic acid (AA) is metabolized by the cytochrome P450 4A (CYP4A) enzymes in cerebral arteries to produce 20-hydroxyeicosatetraenoic acid (20-HETE) and that this compound has effects on cerebral vascular tone that mimic those seen following subarachnoid hemorrhage (SAH). In this regard, 20-HETE is a potent constrictor of cerebral arteries that decreases the…
67
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119
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5
Authors
2.71
FWCI
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Richard J. Roman | Medical College of Wisconsin (US) | — |
| 2 | Marija Renić | Medical College of Wisconsin (US) | |
| 3 | Kathryn M. J. Dunn | Medical College of Wisconsin (US) | — |
| 4 | Kazuhiko Takeuchi | Medical College of Wisconsin (US) | — |
| 5 | Lotfi Hacein‐Bey | Loyola University Medical Cent… (US) Loyola Medicine (US) |
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