Unusual negative charge‐directed fragmentation: collision‐induced dissociation of cyclopentenone oxylipins in negative ion mode

RATIONALE: Oxidized fatty acids, and particularly cyclopentenone oxylipins, are electrophilic metabolites that play diverse physiological roles. Current understanding is limited regarding how ion fragmentation provides essential information about oxylipin structures. In this work, unusual products of the collisional activation of deprotonated cyclopentenone oxylipins were investigated. METHODS: Th…