Interaction of nitric oxide, 20-HETE, and EETs during functi…

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Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex

Article 2008 EN Green

Nitric oxide (NO) modulates vasodilation in cerebral cortex during sensory activation. NO is known to inhibit the synthesis of 20-HETE, which has been implicated in arteriolar constriction during astrocyte activation in brain slices. We tested the hypothesis that the attenuated cerebral blood flow (CBF) response to whisker stimulation seen after NO synthase (NOS) inhibition requires 20-HETE synthe…

81

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6

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6 authors
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1 Xiaoguang Liu Johns Hopkins University (US) Johns Hopkins Medicine (US) +1
2 Chunyuan Li Johns Hopkins University (US) —
3 John Russell Falck The University of Texas Southw… (US)
4 Richard J. Roman Medical College of Wisconsin (US) —
5 David Rae Harder Medical College of Wisconsin (US) —
6 Raymond C. Koehler Johns Hopkins University (US)

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