Contribution of 20-HETE to Vasodilator Actions of Nitric Oxi…

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Contribution of 20-HETE to Vasodilator Actions of Nitric Oxide in the Cerebral Microcirculation

Article 1999 EN

BACKGROUND AND PURPOSE: The present study examined the contributions of a rise in cGMP versus a fall in 20-HETE levels to the vasodilator response to nitric oxide (NO) in the cerebral circulation of the rat. METHODS: Intact rat middle cerebral and basilar arteries were bathed in physiological saline solution containing indomethacin (5 micromol/L) and baicalein (0.5 micromol/L) and pressurized at 9…

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5 authors
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1 Magdalena Alonso‐Galicia Medical College of Wisconsin (US) —
2 Antal G. Hudetz Medical College of Wisconsin (US) —
3 Hui Shen Medical College of Wisconsin (US)
4 David Rae Harder Medical College of Wisconsin (US) —
5 Richard J. Roman Medical College of Wisconsin (US) —

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