Problems Caused by Heterogeneity in Meta-Analysis: A Case St…

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Problems Caused by Heterogeneity in Meta-Analysis: A Case Study of Acupuncture Trials

Article 2013 EN

OBJECTIVES: To illustrate the pitfalls of using meta-analysis to combine estimates of effect in trials that are highly varied and have a high potential for bias. METHODS: We used a random-effects meta-analysis to pool the results of 51 sham-controlled acupuncture trials of chronic pain published in English before 2008 and explored the heterogeneity using meta-regression. We repeated the process on…

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4

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4 authors
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1 Stephanie Louise Prady Corresponding University of York (GB)
2 Jane Burch University of York (GB) —
3 Simon Crouch University of York (GB) —
4 Hugh MacPherson University of York (GB)

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