Homology-extended sequence alignment

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  • DOI 10.1093/nar/gki233
  • PMID https://pubmed.ncbi.nlm.nih.gov/15699183
  • OpenAlex ID W2111937814
  • Type Article
  • Language EN
  • Published 18 Feb 2005
  • Volume 33 (3)
  • Pages 816–824
  • Source Nucleic Acids Research
  • Publisher Oxford University Press
  • FWCI 3.34
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 08 Oct 2026
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Homology-extended sequence alignment

Article 2005 EN Gold

We present a profile-profile multiple alignment strategy that uses database searching to collect homologues for each sequence in a given set, in order to enrich their available evolutionary information for the alignment. For each of the alignment sequences, the putative homologous sequences that score above a pre-defined threshold are incorporated into a position-specific pre-alignment profile. Th…

116

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51

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1

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3.34

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1 Victor A. Simossis Corresponding Vrije Universiteit Amsterdam (NL) —
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