A Transgenic Mouse Model to Study Transsynaptic Regulation o…

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A Transgenic Mouse Model to Study Transsynaptic Regulation of Tyrosine Hydroxylase Gene Expression

Article 1996 EN

Previous studies demonstrated that 9 kb of the rat tyrosine hydroxylase (TH) 5' flanking sequence directed appropriate spatiotemporal expression of a lacZ reporter gene to catecholaminergic cells in the CNS of transgenic mice. In the present study, specificity of transgene expression was further extended to demonstrate cell type-specific functional regulation of lacZ expression using manipulations…

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5 authors
#AuthorInstitutionsORCID
1 Nan Min Queens College, CUNY (US) —
2 TONG HYUB JOH Cornell University (US) Burke Medical Research Institu… (US) —
3 Harriet A. Baker Cornell University (US) Burke Medical Research Institu… (US) —
4 Joseph F. Cubells Cornell University (US) Burke Medical Research Institu… (US)
5 Jin H. Son Corresponding Cornell University (US) Burke Medical Research Institu… (US)

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