1,2-Dichloropropane: metabolism and fate in the rat

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1980
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1,2-Dichloropropane: metabolism and fate in the rat

Article 1980 EN

1. The metabolism of 1,2-dichloropropane in the rat has been investigated. The major urinary metabolite has been isolated and identified as N-acetyl-S-(2-hydroxypropyl)cysteine. Two minor metabolites of 1,2-dichloropropane have been identified as beta-chlorolactate and N-acetyl-S-(2,3-dihydroxypropyl)cysteine. 2. The fate of 1-chloro-2-hydroxypropane, a proposed intermediate metabolite of 1,2-dich…

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1 A. R. Jones The University of Sydney (AU) —
2 Jennifer D. Gibson The University of Sydney (AU) —

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