Stimulation of renin release by prostaglandin E 2 is mediate…
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- DOI 10.1152/ajprenal.00072.2004
- PMID https://pubmed.ncbi.nlm.nih.gov/15113745
- OpenAlex ID W2039857767
- Type Article
- Language EN
- Published 03 May 2004
- Volume 287 (3)
- Pages F427–F433
- Source American Journal of Physiology-Renal Phy…
- Publisher American Physical Society
- FWCI 1.63
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 12 Oct 2026
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Stimulation of renin release by prostaglandin E 2 is mediated by EP 2 and EP 4 receptors in mouse kidneys
Article 2004 EN
PGE(2) is a potent stimulator of renin release. So far, the contribution of each of the four PGE(2) receptor subtypes (EP(1)-EP(4)) in the regulation of renin release has not been characterized. Therefore, we investigated the effects PGE(2) on renin secretion rates (RSR) from isolated, perfused kidneys of EP(1)-/-, EP(2)-/-, EP(3)-/-, EP(4)-/-, and wild-type mice. PGE(2) concentration dependently…
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Frank Schweda | University of Regensburg (DE) | |
| 2 | Jürgen Klar | University of Regensburg (DE) | — |
| 3 | Shuh Narumiya | — | |
| 4 | Rolf Michael Nüsing | Philipps University of Marburg (DE) | — |
| 5 | Armin Kurtz | University of Regensburg (DE) |
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