Effect of Nitric Oxide Synthase Inhibition on the Cerebral V…

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Effect of Nitric Oxide Synthase Inhibition on the Cerebral Vascular Response to Hypercapnia in Primates

Article 1995 EN

BACKGROUND AND PURPOSE: The role of nitric oxide in cerebrovascular response to changes in PCO2 is unclear. In the present study, we assessed responses at two levels of hypercapnia in a primate model before and after blockade of nitric oxide synthesis. METHODS: We compared the effects of two levels of hypercapnia, defined as PCO2 of approximately 70 mm Hg (high-CO2 group, n = 5) and PCO2 of approx…

59

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36

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4

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2.82

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4 authors
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1 Robert W. McPherson Johns Hopkins University (US) Johns Hopkins Medicine (US) +2 —
2 Jeffrey R. Kirsch Johns Hopkins University (US) Johns Hopkins Medicine (US) +2 —
3 Ramsis F. Ghaly Johns Hopkins University (US) Johns Hopkins Medicine (US) +2 —
4 Richard J. Traystman Johns Hopkins University (US) Johns Hopkins Medicine (US) +2 —

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