Nitric oxide-dependent and -independent components of cerebr…
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- DOI 10.1152/ajpregu.1994.266.2.r546
- PMID https://pubmed.ncbi.nlm.nih.gov/7511352
- OpenAlex ID W1916038201
- Type Article
- Language EN
- Published 01 Feb 1994
- Volume 266 (2)
- Pages R546–R552
- Source American Journal of Physiology-Regulator…
- Publisher American Physiological Society
- FWCI 4.69
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 21 Aug 2026
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Nitric oxide-dependent and -independent components of cerebrovasodilation elicited by hypercapnia
Article 1994 EN
We studied the effect of nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase (NOS) inhibitor, on the increases in cerebral blood flow (CBF) elicited by stepwise elevations in arterial partial pressure of CO2 (PaCO2) from normocapnia up to 204 mmHg. Rats were anesthetized with halothane and ventilated. CBF was monitored over the parietal cortex using a laser-Doppler flowmeter. Increasin…
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1 SDGsAuthors & Affiliations
2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Costantino Iadecola | University of Minnesota (US) | |
| 2 | F. Zhang | University of Minnesota (US) | — |
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