Homocysteine induces serum amyloid A3 in osteoblasts via unl…
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- DOI 10.1096/fj.12-208058
- PMID https://pubmed.ncbi.nlm.nih.gov/23085993
- OpenAlex ID W2015536893
- Type Article
- Language EN
- Published 19 Oct 2012
- Volume 27 (2)
- Pages 446–463
- Source The FASEB Journal
- Publisher Wiley
- FWCI 0.77
- Countries 1
- Institutions 3
- Added 24 Jun 2016
- Updated 30 Oct 2026
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Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD‐motifs in collagen
Article 2012 EN
Hyperhomocysteinemia is a risk factor for osteoporotic fractures. Homocysteine (Hcys) inhibits collagen cross-linking and consequently decreases bone extracellular matrix (ECM) quality. Serum amyloid A (A-SAA), an acute-phase protein family, plays an important role in chronic and inflammatory diseases and up-regulates MMP13, which plays an important role in bone development and remodeling. Here, w…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
8 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Roman Thaler | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | |
| 2 | Jochen Zwerina | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | |
| 3 | Monika Rumpler | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | — |
| 4 | Silvia G. Spitzer | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | |
| 5 | Sonja Gamsjaeger | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | |
| 6 | Eleftherios P. Paschalis | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | |
| 7 | Klaus Klaushofer A | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | — |
| 8 | Franz Varga Corresponding | Hanusch Hospital (AT) Ludwig Boltzmann Institute of … (AT) +1 | — |
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