Expression and characterization of glycogen synthase kinase-…
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- DOI 10.1073/pnas.93.19.10228
- PMID https://pubmed.ncbi.nlm.nih.gov/8816781
- OpenAlex ID W1997937533
- Type Article
- Language EN
- Published 17 Sep 1996
- Volume 93 (19)
- Pages 10228–10233
- Source Proceedings of the National Academy of S…
- Publisher National Academy of Sciences
- FWCI 2.28
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells.
Article 1996 EN Green
In these studies we expressed and characterized wild-type (WT) GSK-3 (glycogen synthase kinase-3) and its mutants, and examined their physiological effect on glycogen synthase activity. The GSK-3 mutants included mutation at serine-9 either to alanine (S9A) or glutamic acid (S9E) and an inactive mutant, K85,86MA. Expression of WT and the various mutants in a cell-free system indicated that S9A and…
141
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2.28
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5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Hagit Eldar-Finkelman | University of Washington (US) | |
| 2 | Gretchen M. Argast | University of Washington (US) | — |
| 3 | Orit Foord | University of Washington (US) | — |
| 4 | Edmond H. Fischer | University of Washington (US) | — |
| 5 | Edwin G. Krebs | University of Washington (US) | — |
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