TP receptor-mediated vasoconstriction in microperfused affer…
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- DOI 10.1152/ajprenal.2000.279.2.f302
- PMID https://pubmed.ncbi.nlm.nih.gov/10919850
- OpenAlex ID W1901388521
- Type Article
- Language EN
- Published 01 Aug 2000
- Volume 279 (2)
- Pages F302–F308
- Source American Journal of Physiology-Renal Phy…
- Publisher American Physical Society
- FWCI 2.65
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 16 Oct 2026
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TP receptor-mediated vasoconstriction in microperfused afferent arterioles: roles of O2−and NO
Article 2000 EN
Thromboxane A(2) (TxA(2)) preferentially constricts the renal afferent arteriole. Nitric oxide (NO) modulates vasoconstriction and is rapidly degraded by superoxide radical (O(2)(-)). We investigated the roles of NO and O(2)(-) in rabbit isolated, perfused renal afferent arteriole responses to the TxA(2)/prostaglandin H(2) (TP) receptor agonist U-46,619. U-46,619 (10(-10)-10(-6) M) dose-dependentl…
79
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45
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3
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2.65
FWCI
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3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Christine G. Schnackenberg | Georgetown University Medical … (US) | — |
| 2 | William J. Welch | Georgetown University Medical … (US) | |
| 3 | Christopher Stuart Wilcox | Georgetown University Medical … (US) |
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