Pathophysiology of ANCA-associated vasculitides: are ANCA re…
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- PMID https://pubmed.ncbi.nlm.nih.gov/15025415
- OpenAlex ID W164635967
- Type Article
- Language EN
- Published 01 Dec 2003
- Volume 61 (12)
- Pages 404–7
- Source PubMed
- Publisher National Institutes of Health
- FWCI 0.78
- Countries 1
- Institutions 2
- Added 10 Oct 2025
- Updated 16 Oct 2026
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Pathophysiology of ANCA-associated vasculitides: are ANCA really pathogenic?
Article 2003 EN
The strong relation between antineutrophil cytoplasmic autoantibodies (ANCA) and primary vasculitic syndromes suggests a pathophysiological role for ANCA. Experimental evidence for the pathogenic potential of ANCA has been derived from in vitro studies that demonstrate that ANCA can activate tumour necrosis factor alpha primed neutrophils, monocytes and/or endothelial cells. The binding of ANCA to…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jan Willem Cohen Tervaert | Maastricht University Medical … (NL) Maastricht University (NL) | |
| 2 | Peter Heeringa | — |
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