[Bone adaptation and response to mechanical stress in bone].

To review the progresses in the research of bone adaptation and its mechanisms. The Wolff's law represented early theory of bone adaptation, but the Frost's mechanostat theory developed in 1960s might be the more appropriate theory. Several studies showed that the bone cells including osteoblasts, osteocytes and bone lining cells are the mechanosensitive cells in bone tissue. Forces acting on the…