microRNA and Regulatory Networks of Human Macrophage During …

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microRNA and Regulatory Networks of Human Macrophage During Leishmania major In Vitro Infection

Article 2026 EN Gold

Leishmania (L.) major modulates host microRNA (miR) expression to promote intracellular survival, yet the roles of specific miRs during early infection of human macrophages remain poorly defined. We investigated the dynamic regulation of miR-21-5p and miR-146a-5p in THP-1-derived macrophages infected with L. major over an early post-infection time course (3–48 h), alongside miR-30a-3p and miR-101-…

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UN Sustainable Development Goals
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10 authors
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1 Sara Habouria Tunis University (TN) Institut Pasteur de Tunis (TN) +1
2 Aymen Bali Tunis University (TN) Institut Pasteur de Tunis (TN) +1
3 Aurora Diotallevi University of Urbino (IT)
4 Ali Ben-Cheikh Institut Pasteur de Tunis (TN) Tunis El Manar University (TN)
5 Chiraz Atri Institut Pasteur de Tunis (TN) Tunis El Manar University (TN)
6 Mauro De Santi University of Urbino (IT)
7 Sara Maestrini University of Urbino (IT)
8 Luca Galluzzi University of Urbino (IT)
9 Dhafer Laouini Corresponding Institut Pasteur de Tunis (TN) Tunis El Manar University (TN)
10 Fatma Zahra Guerfali Corresponding Institut Pasteur de Tunis (TN) Tunis El Manar University (TN)
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