Emergence of a genetically distinct cluster of influenza A(H…

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Emergence of a genetically distinct cluster of influenza A(H3N2) viruses within subclade J.2.2 associated with hospitalization during the 2024–2025 season in Auvergne–Rhône–Alpes, France

Article 2026 EN Gold

During the 2024-2025 influenza season in Auvergne-Rhône-Alpes, France, a genetically distinct cluster of A(H3N2) viruses within subclade J.2.2 was found to be significantly overrepresented in hospitalized patients compared with community patients. Circulating mainly in November and December 2024, this genetically distinct cluster harboured HA1:G62R and S145N mutations, both linked to immune escape…

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16 authors
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1 Lama Koumaty Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
2 Stéphanie Dan Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5 —
3 Allan De Clercq Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
4 Grégory Destras Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
5 Hadrien Regue Hospices Civils de Lyon (FR)
6 Antoine Oblette Hospices Civils de Lyon (FR)
7 Adrien Le Meur Hospices Civils de Lyon (FR)
8 Alexandre Gaymard Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
9 Vanessa Escuret Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
10 Maude Bouscambert‐Duchamp Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
11 Emmanuel Chanard — —
12 Margaux Fabre — —
13 Vincent Vieillefond — —
14 Benoît Visseaux —
15 Antonin Bal Corresponding Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5
16 Laurence Josset Corresponding Lyon 1 Université (FR) École Normale Supérieure de Ly… (FR) +5

Data: OpenAlex