Effects of Exogenous Nitric Oxide Gas on Mycobacterium tuber…

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  • DOI 10.64898/2026.08.18.744881
  • OpenAlex ID W7203733123
  • Type Preprint
  • Language EN
  • Published 19 Aug 2026
  • Source bioRxiv (Cold Spring Harbor Laboratory)
  • Publisher Cold Spring Harbor Laboratory
  • Countries 1
  • Institutions 2
  • Added 20 Aug 2026
  • Updated 28 Oct 2026
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Effects of Exogenous Nitric Oxide Gas on Mycobacterium tuberculosis in vitro and in mice

Preprint 2026 EN Green

ABSTRACT In 1992, inhaled NO (iNO) at low doses entered the practice of medicine for cardiopulmonary indications. Recently, iNO at higher doses has been tested in diverse pulmonary infections. However, nothing is known about the ability of exogenous NO gas to kill Mycobacterium tuberculosis (Mtb), the leading cause of death from infection between major viral pandemics. Here we mimicked exposure co…

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1 Xiuju Jiang Cornell University (US)
2 Carl Nathan Corresponding Cornell University (US) Weill Cornell Medicine (US)

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