How do individual monosodium urate depositions respond to ur…

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How do individual monosodium urate depositions respond to urate-lowering therapy? A systematic evaluation using the dual-energy CT modality

Article 2026 EN

OBJECTIVES: To assess how resolution of monosodium urate (MSU) depositions occurs in people with gout during urate-lowering therapy (ULT) by assessing both density reduction of (i) complete and (ii) core part of MSU depositions. Furthermore, to evaluate potential changes in effective atomic numbers as a sign of tophi calcifications. METHODS: Dual-energy CT (DECT) scans of knees and feet were perfo…

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1 Sara Nysom Christiansen Corresponding Glostrup Hospital (DK) Rigshospitalet (DK)
2 Mikkel Østergaard University of Copenhagen (DK) Glostrup Hospital (DK) +1
3 Lene Terslev University of Copenhagen (DK) Glostrup Hospital (DK) +1
4 Ole Slot Aleris Hamlet Hospital (DK)
5 Jakob Møllenbach Møller Herlev Hospital (DK) Copenhagen University Hospital (DK)
6 Henrik Børgesen Herlev Hospital (DK) Copenhagen University Hospital (DK) —
7 Kasper Kjaerulf Gosvig Herlev Hospital (DK) Copenhagen University Hospital (DK)
8 Felix Christoph Müller Herlev Hospital (DK) Copenhagen University Hospital (DK)

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