Spreadsheet-based algorithm for objective assessment of dept…

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Spreadsheet-based algorithm for objective assessment of depth of focus from defocus curves

Article 2026 EN

PURPOSE: To describe and clinically evaluate a spreadsheet-based algorithm for reproducible depth-of-focus (DoF) calculation, incorporating rule-based continuity detection derived from defocus-curve topology. SETTING: Humanitas Clinical and Research Center, Rozzano, Milan, Italy. DESIGN: Methodological description with retrospective clinical validation. METHODS: The algorithm identifies dioptric c…

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5 authors
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1 Antonio Calossi Baylor College of Medicine (US) IRCCS Humanitas Research Hospi… (IT) +1
2 Francesco Calossi University of Florence (IT) —
3 Riccardo Vinciguerra —
4 Douglas Donald Koch Baylor College of Medicine (US)
5 Paolo Vinciguerra IRCCS Humanitas Research Hospi… (IT)

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