Genetic Variant underlying Xanthinuria in a population of Munchkin cats

Hereditary xanthinuria is a genetic disorder of purine metabolism causing xanthinaemia and xanthine crystalluria. Type I xanthinuria is due to mutations in xanthine dehydrogenase (XDH). Type II xanthinuria is caused by mutations in molybdenum cofactor sulfurase (MOCOS). In cats, xanthinuria is a rare but clinically significant disease; however underlying genetic variants have not been described. F…